OrthoSouth’s Dr. John J. Eager Completes First AI-Driven, 3D-Printed Personalized Spine Fusion in the Mid-South Using Carlsmed’s aprevo®

August 28, 2025

MEMPHHIS, TN - OrthoSouth is proud to announce that fellowship-trained spine surgeon Dr. John J. Eager has successfully completed the Mid-South's first spinal fusion using Carlsmed's aprevo® Personalized Spine Implant — an AI-informed, 3D-printed device built to each patient's exact anatomy. The landmark procedure took place at Saint Francis Hospital - Memphis on August 28, 2025.

The aprevo® platform integrates advanced imaging, AI-driven 3D surgical planning, and precision titanium additive manufacturing to produce custom implants that restore targeted spinal alignment, optimize fit, and reduce mechanical complications compared to traditional "off-the-shelf" devices.

Proven Clinical Impact

Data from over 500 patients across multiple centers shows aprevo® delivers:

  • Targeted Alignment: 82% of personalized implants achieved alignment within 5° of surgical goals.
  • Enhanced Graft Contact: 94% average implant-to-endplate contact at one year.
  • Subsidence Mitigation: 96% of personalized implants with zero subsidence at one year.
  • Lower Revision Rates: <2% rate of revision for mechanical complications in adult spinal deformity cases.

"Completing the first aprevo® case in our region was an exciting milestone," says Dr. Eager. "By correcting spinal alignment preoperatively and delivering that plan with a patient-specific implant, we reduce the risk of malalignment and recurrent pain — and give patients the best possible chance at long-term relief."

Personalized Process in Five Steps

  1. CT Imaging to create a detailed 3D spine model.
  2. AI-Based Surgical Planning for alignment restoration and optimal fit.
  3. Surgeon Review & Approval of the personalized implant design.
  4. 3D Printing in Titanium to exact specifications.
  5. Hospital Delivery for use in the planned fusion procedure.

About OrthoSouth:

At OrthoSouth, our goal is to be the best orthopedic practice in the United States, measured by the patient experience. Access, convenience, and a warm, welcoming atmosphere are hallmarks of OrthoSouth's services, which include general, sports medicine, pain and spine care, and subspecialty orthopedics; 8 community-based clinics, 10 physical therapy centers, and 2 outpatient surgery centers; evening hours, early appointment availability, walk-in availability, urgent orthopedic care, Saturday clinic hours, and more. Visit https://orthosouth.org to learn more or to book your appointment online today.

Media Contact:

Melissa Kandel

Director of Marketing

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